Diarrhea

Celiac disease
Cow’s milk protein allergy
Gastroenteritis
Hemolytic uremic syndrome
Inflammatory bowel disease
Toddler’s diarrhea

  • Describe the pathophysiology of osmotic and secretory diarrhea
  • Classify diarrhea based on the underlying pathophysiological mechanisms
  • Recognize that some forms of diarrhea are manifestations of systemic illness

Overview & Foundational Knowledge

First Principles of Gastroenterology. The basis of disease and an approach to management. Fifth edition. Chapter 14. Manifestations of Gastrointestinal Disease in the child. Page 710-719.

http://www.cag-acg.org/uploads/firstprinciples/english.html

http://www.cag-acg.org/uploads/firstprinciples/z_pdf/EN_GAST_14B.pdf

Textbook chapter. Review on acute diarrhea and dehydration.

Penelope H & Dennehy MD. Acute Diarrheal Disease in Children: Epidemiology, Prevention, and Treatment. Infectious Disease Clinics of North America 2005; 19: 585–602.

Overview article on gastroenteritis.

Granado-Villar D, Cunill-De Sautu B & Granados A. Acute Gastroenteritis. Pediatrics in Review 2012; 33: 487.

Overview article on treatment of gastroenteritis and dehydration.

Zella GC & Isreal EJ. Chronic Diarrhea in Children. Pediatrics in Review 2012; 33: 207-218.

Overview on chronic diarrhea. Comprehensive differential diagnosis.

Corrigan Jr JJ & Boineau FG. Hemolytic-Uremic Syndrome. Pediatrics in Review 2001; 22: 365-369.

Brief review on hemolytic uremic syndrome. Not essential but good review.

Hyams JS. Inflammatory Bowel Disease. Pediatrics in Review Vol. 26 No. 9 September 1, 2005, pp. 314–320.

An overview of IBD with a focus on differential diagnosis, presenting features as well as an overview of medications for IBD.

Clinical Resources

Dehydration and Diarrhea

http://www.caringforkids.cps.ca/handouts/dehydration_and_diarrhea

http://www.soinsdenosenfants.cps.ca/handouts/dehydration_and_diarrhea

Parental handout on gastroenteritis, available in English and French.

Oral rehydration therapy and early re-feeding in the management of childhood gastroenteritis

http://www.cps.ca/documents/position/oral-rehydration-therapy

http://www.cps.ca/fr/documents/position/rehydratation-par-voie-orale

Canadian Paediatric Society Position Statement (2006). Clinical resource on treatment of dehydration.

Dehydration.University of Alberta Pedscases.

www.pedscases.com

https://itunes.apple.com/ca/podcast/pedscases.com-pediatrics-for/id330446233

Audio podcast of an approach to assessment and management of dehydration (20min).

Clinical Presentations