Pallor / Anemia

Hemoglobinopathies
Hemolysis
Iron deficiency

  • Describe the anatomy and physiology of the hematopoietic system, including origin, function and structure of each major blood component
  • Describe iron metabolism as it relates to heme production
  • Classify hematologic disease in terms of production, destruction and consumption
  • Describe the physiologic consequences to anemia
  • Identify signs and symptoms of hematologic diseases
  • Demonstrate an approach to the interpretation of a CBC and differential and iron studies

Overview & Foundational Knowledge

Janus J & Moerschel S. Evaluation of anemia in children. American Family Physician 2010; 15(12): 1462-1471.

http://www.aafp.org/afp/2010/0615/p1462.html

Good basic article with flow diagrams capturing diagnosis based on age and MCV.

Hutter JJ. Childhood leukemia.  Pediatrics in Review 2010; 31(6): 234-240. 

Note: ANNL = AML.

Clinical Resources

Lumbar Puncture

www.pedscases.com

Lumbar puncture instruction video (infant). 

Clinical Presentations