{"id":146,"date":"2014-03-17T02:45:01","date_gmt":"2014-03-17T02:45:01","guid":{"rendered":"https:\/\/www.pupdoc.ca\/?page_id=146"},"modified":"2026-01-03T14:21:52","modified_gmt":"2026-01-03T14:21:52","slug":"neonatal-jaundice","status":"publish","type":"page","link":"https:\/\/www.pupdoc.ca\/en\/neonatal-jaundice\/","title":{"rendered":"Neonatal Jaundice"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; inner_shadow=&#8221;on&#8221; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#961622&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header title=&#8221;Neonatal Jaundice&#8221; text_orientation=&#8221;center&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255, 255, 255, 0)&#8221; global_colors_info=&#8221;{}&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover=&#8221;null&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover=&#8221;null&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover=&#8221;null&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover=&#8221;null&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover=&#8221;null&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover=&#8221;null&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover=&#8221;null&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover=&#8221;null&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover=&#8221;null&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover=&#8221;null&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover=&#8221;null&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover=&#8221;null&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover=&#8221;null&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover=&#8221;null&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; inner_shadow=&#8221;on&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#ffffff&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_tabs module_class=&#8221;key-conditions&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; z_index_tablet=&#8221;500&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_tab title=&#8221;Key Conditions&#8221; _builder_version=&#8221;4.25.1&#8243; body_font=&#8221;||||&#8221; tab_font=&#8221;||||&#8221; global_colors_info=&#8221;{}&#8221;]Biliary atresia<br \/>\nBreast feeding jaundice \/ Suboptimal intake jaundice<br \/>\nBreast milk jaundice<br \/>\nHemolytic anemia<br \/>\nKernicterus<br \/>\nPhysiologic jaundice[\/et_pb_tab][et_pb_tab title=&#8221;Foundational Knowledge&#8221; _builder_version=&#8221;4.16&#8243; body_font=&#8221;||||&#8221; tab_font=&#8221;||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Describe liver anatomy and the physiology of bilirubin metabolism and excretion<\/li>\n<li>Describe the functions of the liver and interpret tests of liver function, hepatocellular function and cholestasis<\/li>\n<li>Differentiate between conjugated and unconjugated hyperbilirubinemia<\/li>\n<li>Describe blood group type and antigens, and explain the mechanism whereby blood group incompatibility can affect bilirubin metabolism<\/li>\n<\/ul>\n<p>[\/et_pb_tab][et_pb_tab title=&#8221;Resources&#8221; _builder_version=&#8221;4.27.4&#8243; body_font=&#8221;||||&#8221; tab_font=&#8221;||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<div class='et-learn-more clearfix'>\n\t\t\t\t\t<h3 class='heading-more'>Overview &amp; Foundational Knowledge<span class='et_learnmore_arrow'><span><\/span><\/span><\/h3>\n\t\t\t\t\t<div class='learn-more-content'><table>\n<tbody>\n<tr>\n<td><strong>Bryon J. Hyperbilirubinemia in the Newborn. <em>Pediatrics in Review<\/em> 2011; 32(8): 341-349.<\/strong><\/p>\n<p><a href=\"https:\/\/doi.org\/10.1542\/pir.32-8-341\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1542\/pir.32-8-341<\/a><\/p>\n<p><em>Some foundational knowledge on bilirubin metabolism. Discusses physiologic versus pathologic hyperbilirubinemia. More focus on unconjugated hyperbilirubinemia (e.g. breast milk and breastfeeding jaundice).<\/em><\/td>\n<\/tr>\n<tr>\n<td><strong>Brumbaugh D &amp; Mack C. Conjugated hyperbilirubinemia in children. <em>Pediatrics in Review<\/em> 2012; 33(7): 291-302.<\/strong><\/p>\n<p><a href=\"https:\/\/doi.org\/10.1542\/pir.33-7-291\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1542\/pir.33-7-291<\/a><\/p>\n<p><em>Foundational knowledge. Addresses cholestasis in newborns and older children. Addresses the importance of early diagnosis in newborns. Good visuals.<\/em><\/td>\n<\/tr>\n<tr>\n<td><strong>Jaundice: Newborn to Age 2 months<\/strong><\/p>\n<p><a href=\"https:\/\/doi.org\/10.1542\/pir.2015-0132\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1542\/pir.2015-0132<\/a><\/p>\n<p><em>Pan DH, Rivas Y. Jaundice: Newborn to Age 2 months. Pediatrics in Review 2017; 38(11): 499-510. <\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n\t\t\t\t<\/div><\/p>\n<div class='et-learn-more clearfix'>\n\t\t\t\t\t<h3 class='heading-more'>Clinical Resources<span class='et_learnmore_arrow'><span><\/span><\/span><\/h3>\n\t\t\t\t\t<div class='learn-more-content'><table>\n<tbody>\n<tr>\n<td><strong>Guidelines for the detection, management and prevention of hyperbilirubinemia in term and late preterm newborn infants<\/strong><\/p>\n<p><a href=\"http:\/\/www.cps.ca\/documents\/position\/hyperbilirubinemia-newborn\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.cps.ca\/documents\/position\/hyperbilirubinemia-newborn<\/a><\/p>\n<p><a href=\"http:\/\/www.cps.ca\/fr\/documents\/position\/hyperbilirubinemie-nouveau-nes\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.cps.ca\/fr\/documents\/position\/hyperbilirubinemie-nouveau-nes<\/a><\/p>\n<p><em>Canadian Paediatric Society Position Statement (2007, 2011)<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n\t\t\t\t<\/div>\n<div class='et-learn-more clearfix'>\n\t\t\t\t\t<h3 class='heading-more'>Cards<span class='et_learnmore_arrow'><span><\/span><\/span><\/h3>\n\t\t\t\t\t<div class='learn-more-content'><table>\n<tbody>\n<tr>\n<td><strong>Neonatal Jaundice<\/strong><\/p>\n<p><a href=\"https:\/\/cards.ucalgary.ca\/deck\/83\" target=\"_blank\" rel=\"noopener noreferrer\">Neonatal Jaundice<\/a><\/p>\n<p><em>Canuc-Paeds physician authored, replayable cases<\/em><\/td>\n<\/tr>\n<tr>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n\t\t\t\t<\/div>[\/et_pb_tab][\/et_pb_tabs][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;3.19.9&#8243; background_color=&#8221;#eeeeee&#8221; global_module=&#8221;2263&#8243; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header text_orientation=&#8221;center&#8221; logo_image_url=&#8221;https:\/\/www.pupdoc.ca\/wp-content\/uploads\/2018\/12\/canuc-paeds.png&#8221; _builder_version=&#8221;4.16&#8243; background_color=&#8221;rgba(255, 255, 255, 0)&#8221; background_layout=&#8221;light&#8221; max_width_tablet=&#8221;50px&#8221; custom_padding=&#8221;7px|0px|0px|0px&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; custom_css_main_element=&#8221;max-height: max-content;&#8221; global_colors_info=&#8221;{}&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221;][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; background_color=&#8221;#ffffff&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;||0px|&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;||0px|&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;||0px|&#8221; custom_padding_tablet=&#8221;||0px|&#8221; custom_padding_phone=&#8221;||0px|&#8221; custom_padding_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text module_class=&#8221;menu-clinical-line-height&#8221; _builder_version=&#8221;4.16&#8243; text_line_height=&#8221;1.4em&#8221; custom_margin=&#8221;||0px|&#8221; custom_margin_tablet=&#8221;&#8221; custom_margin_phone=&#8221;&#8221; custom_margin_last_edited=&#8221;on|desktop&#8221; custom_padding=&#8221;||0px|&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/www.pupdoc.ca\/abdominal-pain-abdominal-mass\/\">Abdominal Pain &amp; Abdominal Mass<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/acutely-ill-child\/\">Acutely Ill Child<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/adolescent-health-issues\/\">Adolescent Health Issues<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/altered-loc\/\">Altered Level of Consciousness<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/bruising-bleeding\/\">Bruising \/ Bleeding<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/dehydration\/\">Dehydration<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/development-behavioural-learning-problems\/\">Development \/ Behavioural \/ Learning Problems<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/diarrhea\/\">Diarrhea<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/edema\/\">Edema<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/eye-issues\/\">Eye Issues<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;||0px|&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text module_class=&#8221;menu-clinical-line-height&#8221; _builder_version=&#8221;4.16&#8243; text_line_height=&#8221;1.4em&#8221; custom_margin=&#8221;||0px|&#8221; custom_padding=&#8221;||0px|&#8221; custom_css_main_element=&#8221;margin-bottom: 0px !important;&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/www.pupdoc.ca\/fever\/\">Fever<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/genitourinary-complaints\/\">Genitourinary Complaints<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/growth-problems\/\">Growth Problems<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/headache\/\">Headache<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/inadequately-explained-injury\/\">Inadequately explained injury<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/limp-extremity-pain\/\">Limp \/ Extremity Pain<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/lymphadenopathy\/\">Lymphadenopathy<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/mental-health-concerns\/\">Mental Health Concerns<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/murmur\/\">Murmur<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/neonatal-jaundice\/\"><strong>Neonatal Jaundice<\/strong><\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; background_position=&#8221;top_left&#8221; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text module_class=&#8221;menu-clinical-line-height&#8221; _builder_version=&#8221;4.16&#8243; text_line_height=&#8221;1.4em&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/www.pupdoc.ca\/newborn\/\">Newborn<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/pallor-anemia\/\">Pallor \/ Anemia<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/rash\/\">Rash<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/respiratory-distress-cough\/\">Respiratory distress \/ Cough<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/seizure-paroxysmal-event\/\">Seizure \/ Paroxysmal event<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/sore-ear\/\">Sore Ear<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/sore-throat-sore-mouth\/\">Sore Throat \/ Sore Mouth<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/vomiting\/\">Vomiting<\/a><br \/><a href=\"https:\/\/www.pupdoc.ca\/well-child-care\/\">Well Child Care<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biliary atresia Breast feeding jaundice \/ Suboptimal intake jaundice Breast milk jaundice Hemolytic anemia Kernicterus Physiologic jaundice Describe liver anatomy and the physiology of bilirubin metabolism and excretion Describe the functions of the liver and interpret tests of liver function, hepatocellular function and cholestasis Differentiate between conjugated and unconjugated hyperbilirubinemia Describe blood group type and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-146","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/pages\/146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/comments?post=146"}],"version-history":[{"count":10,"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/pages\/146\/revisions"}],"predecessor-version":[{"id":3036,"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/pages\/146\/revisions\/3036"}],"wp:attachment":[{"href":"https:\/\/www.pupdoc.ca\/en\/wp-json\/wp\/v2\/media?parent=146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}