Seizure / Paroxysmal event

Arrhythmia
Breath-holding spell
Brief Resolved Unexplained Event
Febrile seizure
Epilepsy
Status epilepticus
Syncope
  • Describe the neurophysiology of electrical and chemical signal transmission
  • Discuss the pathophysiology of seizure activity
  • Identify neurologic and non-neurologic causes of paroxysmal events
  • Apply basic principles of pharmacology in the management of seizure
  • Know that arrhythmias in children that may present with sudden collapse and identify common arrhythmias of childhood

Overview & Foundational Knowledge

Learn Pediatrics: Approach to Syncope: is it cardiac or not.

http://learn.pediatrics.ubc.ca/body-systems/cardiology/approach-to-syncope-is-it-cardiac-or-not/

Clinical overview: very practical. Includes definition, common conditions, life threatening conditions and other conditions. Also covers differential diagnosis, questions to ask on history, physical examination findings, investigations. There is a good chart for investigations of syncope.

Seizures in Children Anthony Fine, Elaine C. Wirrell; Seizures in Children. Pediatr Rev July 2020; 41 (7): 321–347.

https://doi.org/10.1542/pir.2019-0134

A good overview of an approach to seizures and epilepsy. Note that the nomenclature for epilepsy syndromes has been recently updated so terminology may be out of date.

Evaluation of First Seizure and Newly Diagnosed Epilepsy Wirrell E. Evaluation of First Seizure and Newly Diagnosed Epilepsy. Continuum (Minneap Minn). 2022 Apr 1;28(2):230-260.

https://doi.org/10.1212/con.0000000000001074

A similar article to the one above but with updated terms for epilepsy syndromes.

Febrile Seizures Gupta A. Febrile Seizures. Continuum (Minneap Minn). 2016 Feb;22(1 Epilepsy):51-9.

https://doi.org/10.1212/con.0000000000000274

A very good review of febrile seizures.

Clinical Resources

Emergency management of the paediatric patient with convulsive status epilepticus CPS position statement.

https://cps.ca/documents/position/emergency-management-of-the-paediatric-patient-with-convulsive-status-epilepticus

Updated CPS guideline on management of status epilepticus

Seizure Types and Epilepsy Pedscases Podcast

https://www.pedscases.com/seizure-types-and-epilepsy

A good overview of approach to seizures and epilepsy.

Status Epilepticus Pedscases

https://pedscases.com/sites/default/files/Status%20Epilepticus.pdf

A good overview of status epilepticus

Febrile Seizures Pedscases

https://pedscases.com/sites/default/files/Febrile%20Seizures.pdf

A good overview of febrile seizures

Syncope Gilpin K, Goode Z. Syncope. Pediatr Rev. 2024 Oct 1;45(10):606-608.

https://doi.org/10.1542/pir.2023-006053

An up-to-date summary of Syncope

Types of Arrhythmia in Children

https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia/types-of-arrhythmia-in-children

The American Heart Association’s page outlines various types of pediatric arrhythmias

Brief Resolved Unexplained Events (Formerly Apparent Life-Threatening Events) and Evaluation of Lower Risk infants. Tieder JS, Bonkowski JL and the Subcommittee on Apparent Life Threatening Events. AAP Clinical Practice Guideline Pediatrics. May 2016. 137(5), e1-e33.

http://pediatrics.aappublications.org/content/early/2016/04/21/peds.2016-0590

Clinical guidelines describing new terminology and approach to assessment and diagnosis.

Febrile Seizures. Guideline for the Neurodiagnostic Evaluation of the Child With a Simple Febrile Seizure. Pediatrics . 2011 Feb;127(2):389-94. doi: 10.1542/peds.2010-3318.

https://doi.org/10.1542/peds.2010-3318

Clinical practice guidelines from the American Academy of Pediatrics.

Cards

Seizure / Paroxysmal Event

Seizure / Paroxysmal Event Diagnosis

Canuc-Paeds physician authored, replayable cases