Pallor / Anemia

Iron deficiency

  • Describe the anatomy and physiology of the hematopoietic system, including origin, function and structure of each major blood component
  • Describe iron metabolism as it relates to heme production
  • Classify hematologic disease in terms of production, destruction and consumption
  • Describe the physiologic consequences to anemia
  • Identify signs and symptoms of hematologic diseases
  • Demonstrate an approach to the interpretation of a CBC and differential and iron studies

Overview & Foundational Knowledge

Janus J & Moerschel S. Evaluation of anemia in children. American Family Physician 2010; 15(12): 1462-1471.

Good basic article with flow diagrams capturing diagnosis based on age and MCV.

Clinical Resources

Lumbar Puncture

Lumbar puncture instruction video (infant).

Virtual Patients or Cases

PedsCases: A Learning Module for the Approach to Pediatric Anemia. Novak C, Forbes K, Gill P. PedsCases: a learning module for the approach to pediatric anemia. MedEdPORTAL Publications. 2016;12:10319.

Two part podcast on approach to pediatric anemia. Learning module includes short vignettes and self-test questions. Podcasts also available on

Clinical Presentations