Neonatal Jaundice

Biliary atresia
Breast feeding jaundice / Suboptimal intake jaundice
Breast milk jaundice
Hemolytic anemia
Kernicterus
Physiologic jaundice
  • Describe liver anatomy and the physiology of bilirubin metabolism and excretion
  • Describe the functions of the liver and interpret tests of liver function, hepatocellular function and cholestasis
  • Differentiate between conjugated and unconjugated hyperbilirubinemia
  • Describe blood group type and antigens, and explain the mechanism whereby blood group incompatibility can affect bilirubin metabolism

Overview & Foundational Knowledge

Bryon J. Hyperbilirubinemia in the Newborn. Pediatrics in Review 2011; 32(8): 341-349.

Some foundational knowledge on bilirubin metabolism. Discusses physiologic versus pathologic hyperbilirubinemia. More focus on unconjugated hyperbilirubinemia (e.g. breast milk and breastfeeding jaundice).

Brumbaugh D & Mack C. Conjugated hyperbilirubinemia in children. Pediatrics in Review 2012; 33(7): 291-302.

Foundational knowledge. Addresses cholestasis in newborns and older children. Addresses the importance of early diagnosis in newborns. Good visuals.

Jaundice: Newborn to Age 2 months

https://doi.org/10.1542/pir.2015-0132

Pan DH, Rivas Y. Jaundice: Newborn to Age 2 months. Pediatrics in Review 2017; 38(11): 499-510.

Clinical Resources

Guidelines for the detection, management and prevention of hyperbilirubinemia in term and late preterm newborn infants

http://www.cps.ca/documents/position/hyperbilirubinemia-newborn

http://www.cps.ca/fr/documents/position/hyperbilirubinemie-nouveau-nes

Canadian Paediatric Society Position Statement (2007, 2011)

Cards

Neonatal Jaundice

Neonatal Jaundice

Canuc-Paeds physician authored, replayable cases